Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122496 | 0.91 | ACE (0.34) | ADRB2ADRB1ADRB3CHRM1TBXA2R | |
| SCHEMBL20122467 | 0.88 | TACR1 (0.36) | CHRM1TBXA2RADRA1AFOLH1 | |
| SCHEMBL20122542 | 0.87 | — | — | |
| SCHEMBL20122464 | 0.87 | — | — | |
| SCHEMBL20122554 | 0.86 | — | — | |
| SCHEMBL20122593 | 0.86 | — | — | |
| SCHEMBL20122518 | 0.86 | — | — | |
| SCHEMBL20122516 | 0.86 | ADRB2 (0.41) | ADRB2ADRB1ADRB3 | |
| SCHEMBL20122394 | 0.85 | KMT2A (0.42) | ADRB2ADRB1ADRB3 | |
| SCHEMBL20122556 | 0.85 | ADRB2 (0.39) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963428-B1 | Bucillamine prodrugs, pharmaceutical compositions thereof, and methods of use | Nguyen, Mark Quang (US) | 2018-05-08 | — | — | US | disclosed |