Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122362 | 0.91 | ACE (0.42) | MMEACEACE2TACR1PPARA | |
| SCHEMBL20122478 | 0.90 | KMT2A (0.43) | MMEACEACE2ALDH1A1PPARA | |
| SCHEMBL20122488 | 0.89 | ALDH1A1 (0.42) | MMEALDH1A1TACR1PPARACYP1A2 | |
| SCHEMBL20122571 | 0.86 | ACE (0.41) | MMEACEACE2ALDH1A1CYP1A2 | |
| SCHEMBL20122543 | 0.85 | MME (0.33) | MMEACEACE2CYP1A2CYP2C9 | |
| SCHEMBL20122568 | 0.82 | CYP1A2 (0.38) | MMEACEACE2ALDH1A1CYP1A2 | |
| SCHEMBL20122567 | 0.82 | MME (0.33) | MMEACEACE2 | |
| SCHEMBL20122586 | 0.82 | ACE (0.40) | MMEACEACE2 | |
| SCHEMBL20122361 | 0.81 | MME (0.31) | MMEACEACE2 | |
| SCHEMBL20122569 | 0.80 | CYP1A2 (0.33) | MMEACEACE2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963428-B1 | Bucillamine prodrugs, pharmaceutical compositions thereof, and methods of use | Nguyen, Mark Quang (US) | 2018-05-08 | — | — | US | disclosed |