Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.31 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122442 | 0.89 | ACE (0.40) | ACEMMEACE2FOLH1NAALAD2 | |
| SCHEMBL20122573 | 0.89 | ACE (0.40) | ACEMMEACE2FOLH1NAALAD2 | |
| SCHEMBL20122577 | 0.88 | ACE (0.39) | ACEMMEACE2FOLH1NAALAD2 | |
| SCHEMBL20122440 | 0.88 | ACE (0.39) | ACEMMEACE2FOLH1NAALAD2 | |
| SCHEMBL20122574 | 0.86 | ACE (0.38) | ACEMMEACE2FOLH1 | |
| SCHEMBL20122439 | 0.86 | ACE (0.38) | ACEMMEACE2FOLH1 | |
| SCHEMBL18650309 | 0.86 | ALDH1A1 (0.41) | ACEFOLH1NAALAD2 | |
| SCHEMBL18650310 | 0.86 | ALDH1A1 (0.41) | ACEFOLH1NAALAD2 | |
| SCHEMBL20122576 | 0.82 | ACE (0.47) | ACEMMEACE2 | |
| SCHEMBL20122438 | 0.82 | ACE (0.47) | ACEMMEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963428-B1 | Bucillamine prodrugs, pharmaceutical compositions thereof, and methods of use | Nguyen, Mark Quang (US) | 2018-05-08 | — | — | US | disclosed |