Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2627828 | 0.80 | CYP2C19 (0.40) | CYP2C19LOXLOXL2KDM4ENPC1 | |
| SCHEMBL31691911 | 0.77 | CYP2C19 (0.38) | CYP2C19LOXLOXL2KDM4ENPC1 | |
| SCHEMBL12963783 | 0.76 | MKNK1 (0.40) | — | |
| SCHEMBL21718479 | 0.76 | CNR2 (0.35) | CYP2C19KDM4EMAPT | |
| SCHEMBL12963788 | 0.74 | NPC1 (0.45) | KDM4ENPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL22065025 | 0.73 | NPC1 (0.30) | NPC1 | |
| SCHEMBL1478401 | 0.72 | CYP2C19 (0.48) | CYP2C19LOXLOXL2KDM4ENPC1 | |
| SCHEMBL21719222 | 0.72 | SIRT6 (0.38) | — | |
| SCHEMBL15483278 | 0.70 | LOX (0.49) | LOXLOXL2NPC1MAPTRAB9A | |
| SCHEMBL20122652 | 0.70 | HMGCR (0.34) | CYP2C19HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963445-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2018-05-08 | — | — | US | disclosed |