Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21278137 | 0.89 | SIGMAR1 (0.69) | SIGMAR1 | |
| SCHEMBL16208532 | 0.85 | SIGMAR1 (0.73) | SIGMAR1 | |
| SCHEMBL17583783 | 0.84 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL16197424 | 0.83 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL16197087 | 0.82 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL16208506 | 0.81 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL5380065 | 0.80 | SIGMAR1 (0.64) | SIGMAR1 | |
| SCHEMBL16208524 | 0.80 | SIGMAR1 (0.78) | SIGMAR1 | |
| SCHEMBL16197413 | 0.80 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL16197810 | 0.80 | SIGMAR1 (1.00) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963453-B2 | Substituted pyrazino[1,2-a]indoles as sigma receptor activity modulators | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 2018-05-08 | — | — | US | disclosed |