Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122710 | 0.81 | MEN1 (0.34) | BRD4DYRK1A | |
| SCHEMBL22474560 | 0.80 | DYRK1A (0.40) | DYRK1A | |
| SCHEMBL20122718 | 0.79 | BRD4 (0.34) | BRD4DYRK1A | |
| SCHEMBL22474556 | 0.70 | DYRK1A (0.41) | DYRK1A | |
| SCHEMBL20122724 | 0.67 | DYRK1A (0.50) | DYRK1A | |
| SCHEMBL20123032 | 0.66 | DYRK1A (0.41) | DYRK1A | |
| SCHEMBL21808613 | 0.66 | DYRK1A (0.46) | DYRK1A | |
| SCHEMBL29756325 | 0.66 | DYRK1A (0.41) | DYRK1A | |
| SCHEMBL20122909 | 0.65 | CREBBP (0.42) | BRD4DYRK1A | |
| SCHEMBL30664263 | 0.65 | CREBBP (0.42) | BRD4DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3792262-A1 | SUBSTITUTED PYRIDO[3,4-B]INDOLES FOR THE TREATMENT OF CARTILAGE DISORDERS | SANOFI (FR) | 2021-03-17 | — | — | EP | disclosed |
| EP-3318563-A1 | SUBSTITUTED PYRIDO[3,4-B]INDOLES FOR THE TREATMENT OF CARTILAGE DISORDERS | SANOFI (FR) | 2018-05-09 | — | — | EP | disclosed |