Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR39 | O43194 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22474563 | 0.76 | PRKAB2 (0.42) | — | |
| SCHEMBL30664132 | 0.76 | PRKAB2 (0.42) | — | |
| SCHEMBL20122734 | 0.67 | PRKAB2 (0.43) | — | |
| SCHEMBL30664159 | 0.65 | PRKAB2 (0.44) | — | |
| SCHEMBL30664205 | 0.62 | DYRK1A (0.49) | — | |
| SCHEMBL20123030 | 0.62 | DYRK1A (0.49) | — | |
| SCHEMBL20351072 | 0.58 | IDO1 (0.38) | GPR39 | |
| SCHEMBL20122732 | 0.54 | PRKAB2 (0.48) | — | |
| SCHEMBL29817742 | 0.53 | MAPT (0.53) | — | |
| SCHEMBL25783627 | 0.52 | IDO1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318563-A1 | SUBSTITUTED PYRIDO[3,4-B]INDOLES FOR THE TREATMENT OF CARTILAGE DISORDERS | SANOFI (FR) | 2018-05-09 | — | — | EP | disclosed |