Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.63 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.63 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 7/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012168 | 0.86 | HCRTR1 (0.63) | HCRTR1HCRTR2NPC1RAB9A | |
| SCHEMBL2014566 | 0.80 | HCRTR1 (0.64) | HCRTR1HCRTR2SMYD3MAPTSTING1 | |
| SCHEMBL2054138 | 0.80 | HCRTR1 (0.64) | HCRTR1HCRTR2SMYD3MAPTSTING1 | |
| SCHEMBL2011420 | 0.79 | HCRTR1 (0.65) | HCRTR1HCRTR2SMYD3STING1 | |
| SCHEMBL2011075 | 0.79 | HCRTR1 (0.62) | HCRTR1HCRTR2SMYD3MAPTSTING1 | |
| SCHEMBL2053609 | 0.78 | HCRTR1 (0.64) | HCRTR1HCRTR2SMYD3STING1L3MBTL1 | |
| SCHEMBL2012845 | 0.78 | HCRTR1 (0.64) | HCRTR1HCRTR2SMYD3STING1L3MBTL1 | |
| SCHEMBL2013557 | 0.78 | HCRTR1 (0.64) | HCRTR1HCRTR2SMYD3MAPTSTING1 | |
| SCHEMBL2054242 | 0.78 | HCRTR1 (0.61) | HCRTR1HCRTR2SMYD3MAPTKLKB1 | |
| SCHEMBL2014489 | 0.78 | HCRTR1 (0.61) | HCRTR1HCRTR2SMYD3MAPTKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | claimed |
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |