Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | BCL6 | P41182 | 2/20 | 0.32 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30664241 | 0.89 | BCL6 (0.35) | KDM4EDYRK1ALMNAHDAC1HDAC6 | |
| SCHEMBL20123041 | 0.89 | BCL6 (0.35) | KDM4EDYRK1ALMNAHDAC1HDAC6 | |
| SCHEMBL29756577 | 0.77 | BCL6 (0.37) | DYRK1AHDAC1HDAC6GRM2BCL6 | |
| SCHEMBL30664269 | 0.77 | KDM4E (0.45) | KDM4EDYRK1ALMNAHASPINDYRK2 | |
| SCHEMBL20122947 | 0.77 | KDM4E (0.45) | KDM4EDYRK1ALMNAHASPINDYRK2 | |
| SCHEMBL20123079 | 0.76 | HDAC1 (0.35) | DYRK1AHDAC1HDAC6HASPINDYRK2 | |
| SCHEMBL30664229 | 0.76 | HDAC1 (0.35) | DYRK1AHDAC1HDAC6HASPINDYRK2 | |
| SCHEMBL30664207 | 0.73 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL20122950 | 0.73 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL20123072 | 0.72 | CRHR1 (0.38) | KDM4EDYRK1AHDAC1HDAC6CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318563-A1 | SUBSTITUTED PYRIDO[3,4-B]INDOLES FOR THE TREATMENT OF CARTILAGE DISORDERS | SANOFI (FR) | 2018-05-09 | — | — | EP | disclosed |