SCHEMBL20123128

SCHEMBL20123128

C=CC1=C(C=C)C2(c3ccccc3-c3c(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)cccc32)c2ccc3c(oc4ccccc43)c21

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.33
PRKDC P78527 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17879462 0.87 ALOX5 (0.36) ALOX5PRKDC
SCHEMBL16491882 0.80 ALOX5 (0.31) ALOX5
SCHEMBL17279379 0.79 ALOX5 (0.39) ALOX5PRKDC
SCHEMBL20715123 0.78 ALOX5 (0.45) ALOX5PRKDC
SCHEMBL17855042 0.77 ALOX5 (0.36) ALOX5PRKDC
SCHEMBL17855040 0.76 ALOX5 (0.35) ALOX5PRKDC
SCHEMBL17034818 0.76 ALOX5 (0.36) ALOX5PRKDC
SCHEMBL17381059 0.75 ALOX5 (0.36) ALOX5PRKDC
SCHEMBL15678671 0.75 ALOX5 (0.54) ALOX5PRKDC
SCHEMBL18562971 0.74 ALOX5 (0.35) ALOX5PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3033405-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-05-09 EP disclosed