Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5436492 | 0.87 | POLB (0.77) | ALDH1A1POLBNPC1RAB9AMEN1 | |
| SCHEMBL10046076 | 0.87 | POLB (0.76) | ALDH1A1POLBRAB9AMEN1KMT2A | |
| SCHEMBL17897623 | 0.81 | NR1H2 (0.59) | ALDH1A1POLBNPC1RAB9ATSHR | |
| SCHEMBL14414984 | 0.80 | ALDH1A1 (0.58) | ALDH1A1POLBNPC1RAB9AMEN1 | |
| SCHEMBL14094848 | 0.79 | POLB (0.53) | ALDH1A1POLBRAB9AMEN1KMT2A | |
| SCHEMBL17946077 | 0.79 | ALDH1A1 (0.75) | ALDH1A1POLBMEN1KMT2ATSHR | |
| SCHEMBL14560525 | 0.78 | POLB (0.72) | ALDH1A1POLBNPC1MEN1KMT2A | |
| SCHEMBL13159367 | 0.77 | ALDH1A1 (0.71) | ALDH1A1POLBMEN1KMT2ATSHR | |
| SCHEMBL10491219 | 0.76 | POLB (0.75) | ALDH1A1POLBNPC1RAB9AMEN1 | |
| SCHEMBL15046557 | 0.76 | CHRM2 (0.60) | ALDH1A1NPC1RAB9ATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2749566-B1 | SOLID-PHASE CARRIER FOR AMINATED OLIGONUCLEOTIDE | AIST (JP) | 2018-05-09 | — | — | EP | disclosed |