Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11985003 | 0.88 | NPC1 (0.52) | POLBHPGDMAPTCYP1A2CYP2C9 | |
| SCHEMBL3445622 | 0.80 | MAPT (0.62) | POLBHPGDMAPTCYP1A2CYP2C9 | |
| SCHEMBL13788773 | 0.80 | MAPT (0.58) | POLBHPGDMAPTCYP1A2CYP2C9 | |
| SCHEMBL9362200 | 0.80 | HDAC1 (0.68) | MAPTHDAC1HDAC8HDAC6NPC1 | |
| SCHEMBL10895501 | 0.78 | KCNMA1 (0.69) | POLBHPGDMAPTCYP1A2HDAC1 | |
| SCHEMBL31670343 | 0.78 | KCNMA1 (0.69) | POLBHPGDMAPTCYP1A2HDAC1 | |
| SCHEMBL12355510 | 0.77 | CYP1A2 (0.55) | POLBHPGDMAPTCYP1A2CYP2C9 | |
| SCHEMBL1258663 | 0.77 | POLB (0.51) | POLBHPGDMAPTCYP1A2CYP2C9 | |
| SCHEMBL12347501 | 0.77 | MAPT (0.55) | POLBHPGDMAPTCYP1A2CYP2C9 | |
| SCHEMBL14900902 | 0.77 | POLB (0.72) | POLBHPGDMAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588144-B1 | DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY | VENTANA MED SYST INC (US) | 2018-05-09 | — | — | EP | disclosed |