Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16587944 | 0.85 | KAT2B (0.36) | KAT2BBAZ2BPIK3CDACACBL3MBTL1 | |
| SCHEMBL13319823 | 0.82 | PIK3CD (0.36) | KAT2BBAZ2BPIK3CDACACBL3MBTL1 | |
| SCHEMBL6580932 | 0.82 | KAT2B (0.35) | KAT2BBAZ2BPIK3CDACACBL3MBTL1 | |
| SCHEMBL6578556 | 0.82 | KAT2B (0.35) | KAT2BBAZ2BPIK3CDACACBL3MBTL1 | |
| SCHEMBL20388745 | 0.81 | EPHX1 (0.42) | — | |
| SCHEMBL7601636 | 0.79 | PIK3CD (0.35) | KAT2BBAZ2BPIK3CDACACBHRH3 | |
| SCHEMBL5985348 | 0.79 | PIK3CD (0.35) | KAT2BBAZ2BPIK3CDACACBHRH3 | |
| SCHEMBL19228020 | 0.79 | PIK3CD (0.35) | KAT2BBAZ2BPIK3CDACACBL3MBTL1 | |
| SCHEMBL5987438 | 0.79 | PIK3CD (0.35) | KAT2BBAZ2BPIK3CDACACBHRH3 | |
| SCHEMBL73973 | 0.79 | KAT2B (0.42) | KAT2BBAZ2BPIK3CDACACBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |