Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1023586 | 0.91 | KAT2B (0.43) | KAT2BBAZ2BACACBPIK3CDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL3966985 | 0.89 | KAT2B (0.42) | KAT2BBAZ2BACACBL3MBTL1EPHX1 | |
| SCHEMBL7055943 | 0.88 | PDE4D (0.38) | KAT2BBAZ2BACACBPDE4DPDE4A | |
| SCHEMBL1078014 | 0.84 | EPHX1 (0.39) | EPHX1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL697519 | 0.84 | — | — | |
| SCHEMBL16587944 | 0.82 | KAT2B (0.36) | KAT2BBAZ2BACACBPIK3CDL3MBTL1 | |
| SCHEMBL698655 | 0.79 | — | — | |
| SCHEMBL305953 | 0.79 | EPHX1 (0.50) | EPHX1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL10344338 | 0.79 | EPHX1 (0.45) | ACACBEPHX1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL6580932 | 0.79 | KAT2B (0.35) | KAT2BBAZ2BACACBPIK3CDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658639-B2 | N-substituted-cyclic amino derivative | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2014-02-25 | — | — | US | claimed |
| US-20120122773-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-05-17 | — | — | US | claimed |
| EP-2447264-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2012-05-02 | — | — | EP | claimed |
| US-7687490-B2 | 2-thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2010-03-30 | — | — | US | claimed |
| EP-1870412-A1 | 2-THIOETHENYL CARBAPENEM DERIVATIVE | MEIJI SEIKA KAISHA LTD. (JP) | 2007-12-26 | — | — | EP | claimed |
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-01-04 | — | — | US | claimed |
| EP-4201942-A1 | BORACIC ACID COMPOUND | Phaeno Therapeutics Co., Ltd. (CN) | 2023-06-28 | — | — | EP | disclosed |
| CN-109608436-B | Substituted methyl formyl reagents and methods of using same to improve physicochemical and/or pharmacokinetic properties of compounds | 斯法尔制药私人有限公司 | 2022-10-11 | — | — | CN | disclosed |
| US-9914719-B2 | Hydroxybenzamide derivatives and their use as inhibitors of HSP90 | ASTEX THERAPEUTICS LTD. (GB) | 2018-03-13 | — | — | US | disclosed |
| US-9527844-B2 | Naphthyridine derivative compounds | ASTEX THERAPEUTICS LIMITED (GB) | 2016-12-27 | — | — | US | disclosed |
| EP-2170849-B1 | OXAZOLE TYROSINE KINASE INHIBITORS | SAREUM LTD (GB) | 2016-12-21 | — | — | EP | disclosed |
| US-9464071-B2 | Pyrazolyl quinoxaline kinase inhibitors | ASTEX THERAPEUTICS LTD (GB) | 2016-10-11 | — | — | US | disclosed |
| US-9458158-B2 | Bicyclic heterocycle compounds and their uses in therapy | ASTEX THERAPEUTICS LIMITED (GB) | 2016-10-04 | — | — | US | disclosed |
| EP-0584663-A2 | Process for the preparation of tetrahydropyran-4-carboxylic acid and his esters | BASF Aktiengesellschaft (DE) | 1994-03-02 | — | — | EP | disclosed |
| EP-0546409-A1 | Method for the preparation of tetrahydropyrancarboxylic esters | BASF Aktiengesellschaft (DE) | 1993-06-16 | — | — | EP | disclosed |
| EP-0546395-A1 | Method for the preparation of carboxylic esters | BASF Aktiengesellschaft (DE) | 1993-06-16 | — | — | EP | disclosed |
| EP-0546396-A1 | Method for the preparation of 4-hydroxymethyltetrahydropyrans | BASF Aktiengesellschaft (DE) | 1993-06-16 | — | — | EP | disclosed |
| EP-0284969-B1 | PROCESS FOR THE PREPARATION OF TETRAHYDROPYRAN-4-CARBOXYLIC ACID ESTERS | BASF Aktiengesellschaft (DE) | 1990-11-28 | — | — | EP | disclosed |
| EP-0219091-B1 | PYRAN DERIVATIVES AND PROCESS FOR THEIR PREPARATION | BASF Aktiengesellschaft (DE) | 1989-04-26 | — | — | EP | disclosed |
| EP-0284969-A2 | Process for the preparation of tetrahydropyran-4-carboxylic acid esters | BASF Aktiengesellschaft (DE) | 1988-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MTAP, BLVRB, BPGM | KAT2B 2884/4885BAZ2B 101/4885ACACB 2983/4885 |
| US-20120122773-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | REN, AGTR1, AGTR2 | KAT2B 1443/4885BAZ2B 1360/4885ACACB 2246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.