Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166860 | 0.91 | ATM (0.57) | ATMALDH1A1KMT2ALMNAGAA | |
| SCHEMBL15142912 | 0.83 | TSHR (0.51) | ATMALDH1A1KMT2ALMNAGAA | |
| SCHEMBL65273 | 0.81 | TDP1 (0.55) | ATMALDH1A1KMT2ALMNAGAA | |
| SCHEMBL12994219 | 0.81 | ALDH1A1 (0.56) | ATMALDH1A1KMT2ALMNAGAA | |
| SCHEMBL63719 | 0.81 | TDP1 (0.54) | ATMALDH1A1KMT2ALMNAGAA | |
| SCHEMBL16666715 | 0.81 | ATM (0.51) | ATMALDH1A1KMT2ALMNAGAA | |
| SCHEMBL421739 | 0.80 | ATM (0.54) | ATMALDH1A1KMT2ALMNAGAA | |
| SCHEMBL21975629 | 0.80 | ATM (0.46) | ATMALDH1A1KMT2ALMNAGAA | |
| SCHEMBL21259176 | 0.79 | ATM (0.47) | ATMALDH1A1KMT2ALMNAGAA | |
| SCHEMBL15148099 | 0.79 | ALDH1A1 (0.56) | ATMALDH1A1KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |