Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206609 | 0.91 | TSHR (0.68) | TSHRELANEIDO1AGXTCETP | |
| SCHEMBL18822906 | 0.86 | TSHR (0.53) | TSHRELANEIDO1AGXTCETP | |
| SCHEMBL5379773 | 0.85 | TSHR (0.61) | TSHRELANEIDO1AGXTCETP | |
| SCHEMBL9939654 | 0.83 | TSHR (0.50) | TSHRELANECETP | |
| SCHEMBL27524435 | 0.83 | TSHR (0.59) | TSHRELANEIDO1AGXTCETP | |
| SCHEMBL79996 | 0.83 | TSHR (0.63) | TSHRELANEIDO1AGXTCETP | |
| SCHEMBL12239114 | 0.82 | TSHR (0.62) | TSHRELANECETPNPC1RAB9A | |
| SCHEMBL2301938 | 0.82 | TSHR (0.57) | TSHRELANEIDO1AGXTCETP | |
| SCHEMBL2365443 | 0.82 | TSHR (0.57) | TSHRELANEIDO1CETPSRC | |
| SCHEMBL218693 | 0.82 | TSHR (0.57) | TSHRELANEIDO1AGXTCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |