Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600940 | 0.88 | CHRM1 (0.38) | KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL19220550 | 0.85 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL4166026 | 0.80 | SLC22A2 (0.51) | — | |
| SCHEMBL19220540 | 0.80 | — | — | |
| SCHEMBL19220537 | 0.79 | — | — | |
| SCHEMBL10442768 | 0.79 | HTT (0.38) | — | |
| SCHEMBL2601286 | 0.77 | POLB (0.39) | MAPTALDH1A1 | |
| SCHEMBL4166008 | 0.76 | SLC22A2 (0.49) | — | |
| SCHEMBL2601289 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1 | |
| SCHEMBL4164661 | 0.75 | SLC22A2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |