Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.44 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL871736 | 0.82 | ACHE (0.47) | ACHEMEN1KMT2A | |
| SCHEMBL9493217 | 0.81 | ACHE (0.50) | ACHEMEN1KMT2AHPGDGLA | |
| Ammonia Solution, Strong SCHEMBL9998424 | 0.81 | ACHE (0.55) | ACHEMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL791894 | 0.80 | — | — | |
| SCHEMBL12590855 | 0.79 | ACHE (0.59) | ACHE | |
| SCHEMBL12987284 | 0.79 | ACHE (0.44) | ACHEMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL1416143 | 0.79 | ACHE (0.44) | ACHEMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL26928170 | 0.78 | — | — | |
| SCHEMBL20123338 | 0.78 | — | — | |
| SCHEMBL15223682 | 0.78 | ACHE (0.52) | ACHEMEN1KMT2AKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |