Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21913211 | 0.83 | KDM4E (0.37) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL19054923 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL21415870 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL21913548 | 0.79 | MAPT (0.40) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL19233653 | 0.75 | GAA (0.47) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL18083287 | 0.75 | SMN1; SMN2 (0.55) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL21913921 | 0.73 | KDM4E (0.38) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL19233667 | 0.73 | KDM4E (0.49) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL20124331 | 0.73 | ADORA1 (0.46) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL21101419 | 0.72 | KDM4E (0.40) | KDM4EALDH1A1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318566-A1 | AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS | UDC Ireland Limited (IE) | 2018-05-09 | — | — | EP | disclosed |