Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25638911 | 0.81 | KDM4E (0.43) | KDM4ESMN1; SMN2ATMRAB9AALDH1A1 | |
| SCHEMBL26168128 | 0.78 | SMN1; SMN2 (0.48) | KDM4ESMN1; SMN2ATMRAB9AALDH1A1 | |
| SCHEMBL21913921 | 0.78 | KDM4E (0.38) | KDM4ESMN1; SMN2ATMRAB9AALDH1A1 | |
| SCHEMBL19233667 | 0.75 | KDM4E (0.49) | KDM4ESMN1; SMN2ATMRAB9AALDH1A1 | |
| SCHEMBL18083287 | 0.74 | SMN1; SMN2 (0.55) | KDM4ESMN1; SMN2ATMRAB9AALDH1A1 | |
| SCHEMBL26168133 | 0.73 | KDM4E (0.51) | KDM4ESMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL20124326 | 0.72 | KDM4E (0.43) | KDM4ESMN1; SMN2ATMRAB9AALDH1A1 | |
| SCHEMBL13317091 | 0.72 | KDM4E (0.47) | KDM4ESMN1; SMN2ALDH1A1MAPTTP53 | |
| SCHEMBL26168138 | 0.72 | SMN1; SMN2 (0.42) | KDM4ESMN1; SMN2ATMRAB9AALDH1A1 | |
| SCHEMBL12799837 | 0.71 | ATM (0.53) | KDM4ESMN1; SMN2ATMRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2993215-B1 | Azabenzimidazo[2,1-a]benzimidazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2019-06-19 | — | — | EP | disclosed |