SCHEMBL20124355

SCHEMBL20124355

CCOc1ccc(Cc2cc(C3CC(C)CC(O)C3)ccc2Cl)cc1

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 18/20 0.59
SLC5A1 P13866 11/20 0.59
ADRA2A P08913 1/20 0.54
SLC5A11 Q8WWX8 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20124373 0.87 SLC5A2 (0.59) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL20124375 0.85 SLC5A2 (0.45) SLC5A2SLC5A1
SCHEMBL18627346 0.81 SLC5A2 (0.62) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL13448996 0.81 SLC5A2 (0.62) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL17189179 0.81 SLC5A2 (0.62) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18265040 0.79 SLC5A2 (0.60) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL22872101 0.79 SLC5A2 (0.60) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL20124376 0.79 SLC5A2 (0.54) SLC5A2SLC5A1
SCHEMBL18912103 0.79 SLC5A2 (0.54) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL13448533 0.78 SLC5A2 (0.62) SLC5A2SLC5A1ADRA2ASLC5A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2230907-B1 BENZYLPHENYL CYCLOHEXANE DERIVATIVES AND METHODS OF USE THERACOS INC (US) 2018-05-09 EP disclosed