SCHEMBL20124375

SCHEMBL20124375

CCCc1ccc(Cc2cc(C3CC(C)CC(O)C3)ccc2Cl)cc1

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 19/20 0.45
SLC5A1 P13866 14/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21765097 0.92 SLC5A2 (0.44) SLC5A2SLC5A1
SCHEMBL20124374 0.86 SLC5A2 (0.46) SLC5A2SLC5A1
SCHEMBL20124355 0.85 SLC5A2 (0.59) SLC5A2SLC5A1
SCHEMBL23453304 0.84 SLC5A2 (0.39) SLC5A2SLC5A1
SCHEMBL20124376 0.81 SLC5A2 (0.54) SLC5A2SLC5A1
SCHEMBL20124343 0.77 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL20124366 0.77 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL24981125 0.75 SLC5A2 (0.48) SLC5A2SLC5A1
SCHEMBL25665514 0.74 SLC5A2 (0.49) SLC5A2SLC5A1
SCHEMBL24952274 0.74 SLC5A2 (0.36) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2230907-B1 BENZYLPHENYL CYCLOHEXANE DERIVATIVES AND METHODS OF USE THERACOS INC (US) 2018-05-09 EP disclosed