Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 17/20 | 0.74 |
| ▸ | IDO1 | P14902 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20124631 | 0.87 | TDO2 (0.75) | TDO2IDO1 | |
| SCHEMBL16247548 | 0.86 | TDO2 (0.79) | TDO2IDO1 | |
| SCHEMBL16247508 | 0.86 | TDO2 (0.79) | TDO2IDO1 | |
| SCHEMBL17531849 | 0.85 | TDO2 (1.00) | TDO2IDO1 | |
| SCHEMBL16247525 | 0.82 | TDO2 (1.00) | TDO2IDO1 | |
| SCHEMBL16247607 | 0.81 | TDO2 (0.78) | TDO2IDO1 | |
| SCHEMBL17531832 | 0.78 | IDO1 (0.83) | TDO2IDO1 | |
| SCHEMBL16247558 | 0.75 | IDO1 (0.67) | TDO2IDO1 | |
| SCHEMBL16247545 | 0.75 | TDO2 (0.62) | TDO2IDO1 | |
| SCHEMBL17538723 | 0.74 | TDO2 (0.61) | TDO2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970173-B1 | INHIBITORS OF THE KYNURENINE PATHWAY | CURADEV PHARMA PRIVATE LTD (IN) | 2018-05-09 | — | — | EP | disclosed |