Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.60 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.58 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.57 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.57 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2998598 | 1.00 | USP2 (0.65) | USP2HTTP2RY10LPAR5LPAR1 | |
| SCHEMBL2998602 | 1.00 | USP2 (0.65) | USP2HTTP2RY10LPAR5LPAR1 | |
| SCHEMBL15295092 | 1.00 | USP2 (0.65) | USP2HTTP2RY10LPAR5LPAR1 | |
| SCHEMBL14848735 | 0.95 | USP2 (0.59) | USP2HTTP2RY10LPAR5 | |
| SCHEMBL14841801 | 0.95 | USP2 (0.59) | USP2HTTP2RY10LPAR5 | |
| SCHEMBL14841798 | 0.95 | USP2 (0.59) | USP2HTTP2RY10LPAR5 | |
| SCHEMBL4814012 | 0.95 | USP2 (0.59) | USP2HTTP2RY10LPAR5 | |
| SCHEMBL14848905 | 0.95 | USP2 (0.59) | USP2HTTP2RY10LPAR5 | |
| SCHEMBL15295109 | 0.93 | USP2 (0.62) | USP2HTTP2RY10LPAR5LPAR1 | |
| SCHEMBL17237747 | 0.92 | USP2 (0.75) | USP2HTTP2RY10LPAR5LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2830594-B1 | DIETHER BASED BIODEGRADABLE CATIONIC LIPIDS FOR siRNA DELIVERY | SIRNA THERAPEUTICS INC (US) | 2018-05-09 | — | — | EP | disclosed |