SCHEMBL2998602

SCHEMBL2998602

CCCCCCCCC=CCCCCCCCCOCC(O)COCCCCCCCCC=CCCCCCCCC

nearest known ligand 0.73

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.65
HTT P42858 1/20 0.62
P2RY10 O00398 1/20 0.60
LPAR5 Q9H1C0 1/20 0.58
LPAR1 Q92633 3/20 0.57
LPAR3 Q9UBY5 3/20 0.57
SPHK1 Q9NYA1 1/20 0.53
LPAR2 Q9HBW0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2998598 1.00 USP2 (0.65) USP2HTTP2RY10LPAR5LPAR1
SCHEMBL20124691 1.00 USP2 (0.65) USP2HTTP2RY10LPAR5LPAR1
SCHEMBL15295092 1.00 USP2 (0.65) USP2HTTP2RY10LPAR5LPAR1
SCHEMBL14848735 0.95 USP2 (0.59) USP2HTTP2RY10LPAR5
SCHEMBL14841801 0.95 USP2 (0.59) USP2HTTP2RY10LPAR5
SCHEMBL14841798 0.95 USP2 (0.59) USP2HTTP2RY10LPAR5
SCHEMBL4814012 0.95 USP2 (0.59) USP2HTTP2RY10LPAR5
SCHEMBL14848905 0.95 USP2 (0.59) USP2HTTP2RY10LPAR5
SCHEMBL15295109 0.93 USP2 (0.62) USP2HTTP2RY10LPAR5LPAR1
SCHEMBL17237747 0.92 USP2 (0.75) USP2HTTP2RY10LPAR5LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1596670-B1 OILS ENRICHED WITH DIACYLGLYCEROLS AND PHYTOSTEROL ESTERS FOR USE IN THE REDUCTION OF CHOLESTEROL AND TRIGLYCERIDES ENZYMOTEC LTD (IL) 2014-05-07 EP disclosed
US-8507466-B2 Oils enriched with diacylglycerols and phytosterol esters and unit dosage forms thereof for use in therapy ENZYMOTEC LTD. (IL) 2013-08-13 US disclosed
US-20100184734-A1 Oils enriched with diacylglycerols and phytosterol esters and unit dosage forms thereof for use in therapy ENZYMOTEC LTD. 2010-07-22 US disclosed
US-7375135-B2 Fatty acid derivatives; preparation and uses thereof GENFIT (FR) 2008-05-20 US disclosed
EP-1673338-B1 FATTY ACID COMPOUNDS, PREPARATION AND USES THEREOF GENFIT (FR) 2007-09-19 EP disclosed
US-20060252827-A1 Therapeutic use of of acyglycerols and the nitrogen-and sulphur-containing analogues thereof GENFIT (FR) 2006-11-09 US disclosed
US-20060233863-A1 Oils enriched with diacylglycerols and phytosterol esters and unit dosage forms thereof for use in therapy ENZYMOTEC LTD. (IL) 2006-10-19 US disclosed
EP-1673338-A1 FATTY ACID COMPOUNDS, PREPARATION AND USES THEREOF Genfit (FR) 2006-06-28 EP disclosed
US-20060052351-A1 Oils enriched with diacylglycerols and phytosterol esters for use in the reduction of blood cholestrol and triglycerides and oxidative stress ENZYMOTEC LTD. (IL) 2006-03-09 US disclosed
EP-1596670-A2 OILS ENRICHED WITH DIACYLGLYCEROLS AND PHYTOSTEROL ESTERS FOR USE IN THE REDUCTION OF CHOLESTEROL AND TRIGLYCERIDES Enzymotec Ltd. (IL) 2005-11-23 EP disclosed
WO-2004084646-A2 COSMETIC COMPOSITIONS COMPRISING PHYTOSTEROL ESTERS ENZYMOTEC LTD. (IL) 2004-10-07 WO disclosed
US-20040192908-A1 Fatty acid compounds, preparation and uses thereof GENFIT (FR) 2004-09-30 US disclosed
WO-2004069150-A2 OILS ENRICHED WITH DIACYLGLYCEROLS AND PHYTOSTEROL ESTERS FOR USE IN THE REDUCTION OF CHOLESTEROL AND TRIGLYCERIDES ENZYMOTEC LTD. (IL) 2004-08-19 WO disclosed
WO-2003014073-A1 FATTY ACID COMPOUNDS, PREPARATION AND USES THEREOF GENFIT (FR) 2003-02-20 WO disclosed
EP-0685234-B1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU CO LTD (JP) 2000-05-10 EP disclosed
US-6020317-A Glycerol derivative, device and pharmaceutical composition NIPPON SHINYAKU CO. LTD. (JP) 2000-02-01 US disclosed
EP-0685457-B1 GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION NIPPON SHINYAKU CO LTD (JP) 1999-12-15 EP disclosed
US-5705188-A LIPID MIXTURE, ANTITUMOR AGENTS NIPPON SHINYAKU COMPANY, LTD. (JP) 1998-01-06 US disclosed
EP-0685457-A1 GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed
EP-0685234-A1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060252827-A1 Therapeutic use of of acyglycerols and the nitrogen-and sulphur-containing analogues thereof SGMS2, SGMS1, AGK USP2 2389/4885HTT 1822/4885P2RY10 2865/4885
US-20040192908-A1 Fatty acid compounds, preparation and uses thereof FASN, FFAR1, PLIN5 USP2 4008/4885HTT 1016/4885P2RY10 2676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.