Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.60 |
| ▸ | CYCS | P99999 | 4/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 3/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429681 | 0.83 | TOP1 (0.70) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL19718147 | 0.81 | ABCG2 (0.57) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL8907679 | 0.80 | TOP1 (0.52) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL17368875 | 0.80 | TOP1 (0.61) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL10120460 | 0.78 | TOP1 (0.52) | TOP1CYCSABCG2 | |
| SCHEMBL9429433 | 0.77 | TOP1 (0.60) | TOP1CYCSABCG2ENPP2 | |
| SCHEMBL8906606 | 0.77 | TOP1 (0.60) | TOP1CYCSABCG2ENPP2 | |
| SCHEMBL19718141 | 0.76 | MAPK1 (0.51) | TOP1CYCSABCG2 | |
| SCHEMBL16921812 | 0.76 | TOP1 (0.50) | TOP1CYCSABCG2RIPK1HDAC3 | |
| SCHEMBL709532 | 0.76 | TOP1 (1.00) | TOP1CYCSABCG2ENPP2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2814598-B1 | METHOD FOR FUNCTIONALISING CARBON NANO-OBJECTS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2018-05-09 | — | — | EP | disclosed |