Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.60 |
| ▸ | CYCS | P99999 | 4/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906606 | 1.00 | TOP1 (0.60) | TOP1CYCSABCG2BCHEDGAT1 | |
| SCHEMBL8907679 | 0.96 | TOP1 (0.52) | TOP1CYCSABCG2BCHEDGAT1 | |
| SCHEMBL8908782 | 0.86 | TOP1 (0.58) | TOP1CYCSABCG2ENPP2 | |
| SCHEMBL9429267 | 0.82 | TOP1 (0.58) | TOP1CYCSABCG2 | |
| SCHEMBL9429681 | 0.82 | TOP1 (0.70) | TOP1CYCSABCG2ENPP2 | |
| SCHEMBL9429473 | 0.81 | TOP1 (0.54) | TOP1CYCSABCG2ENPP2 | |
| SCHEMBL5896700 | 0.80 | DGAT1 (0.53) | DGAT1GABRA5CD274EGFR | |
| SCHEMBL14174613 | 0.78 | TOP1 (0.79) | TOP1CYCSABCG2ENPP2 | |
| SCHEMBL28152414 | 0.78 | TOP1 (0.79) | TOP1CYCSABCG2ENPP2 | |
| SCHEMBL29354037 | 0.78 | TOP1 (1.00) | TOP1CYCSABCG2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284647-A | Administering for magnetic resonance imaging | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| EP-0336879-A1 | Meso-tetraphenylporphyrin complex compounds,process for their preparation and pharmaceuticals containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-10-11 | — | — | EP | disclosed |