Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8182884 | 0.78 | NR3C2 (0.51) | NR3C2GRM5MMP12SMN1; SMN2ALDH1A1 | |
| SCHEMBL8201930 | 0.78 | NR3C2 (0.42) | NR3C2GRM5MMP12SMN1; SMN2ALDH1A1 | |
| SCHEMBL19751548 | 0.75 | MMP12 (0.45) | NR3C2GRM5MMP12SMN1; SMN2ALDH1A1 | |
| SCHEMBL2075401 | 0.75 | AHR (0.56) | GRM5MCL1KCNH2CA1CA2 | |
| SCHEMBL2483112 | 0.75 | NR3C2 (0.47) | NR3C2GRM5MMP12SMN1; SMN2ALDH1A1 | |
| SCHEMBL3489518 | 0.75 | NR3C2 (0.47) | NR3C2GRM5MMP12ALDH1A1PARP1 | |
| SCHEMBL3488166 | 0.75 | NR3C2 (0.54) | NR3C2GRM5MMP12SMN1; SMN2ALDH1A1 | |
| SCHEMBL1137855 | 0.75 | GRM5 (0.48) | NR3C2GRM5MMP12ALDH1A1PARP1 | |
| SCHEMBL30609076 | 0.75 | NR3C2 (0.47) | NR3C2GRM5MMP12SMN1; SMN2ALDH1A1 | |
| SCHEMBL3488031 | 0.75 | AHR (0.56) | NR3C2GRM5MMP12ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |