⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3284269 | 1.00 | — | — | |
| SCHEMBL2012503 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL7782608 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL7782604 | 0.97 | — | — | |
| SCHEMBL16611527 | 0.86 | LMNA (0.33) | — | |
| SCHEMBL28268520 | 0.82 | — | — | |
| SCHEMBL564860 | 0.80 | — | — | |
| SCHEMBL24283 | 0.80 | — | — | |
| SCHEMBL30452046 | 0.78 | — | — | |
| Water SCHEMBL26089071 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573928-A | 2-aminothiazole derivative or salt thereof | 安斯泰来制药株式会社 | 2017-04-19 | — | — | CN | claimed |
| CN-114369052-A | Synthetic method of 3-aminopyrrolidine dihydrochloride | 赤峰万泽药业股份有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-109152701-B | Dental composition | 登特斯普伊德特雷有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-108135782-B | Dental composition | 登特斯普伊德特雷有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-111902400-A | Aromatic derivatives, process for their preparation and their medical use | 保仕健生物科技(上海)有限公司 | 2020-11-06 | — | — | CN | disclosed |
| EP-2513110-B1 | 1,7-DIAZACARBAZOLES AND THEIR USE IN THE TREATMENT OF CANCER | HOFFMANN LA ROCHE (CH) | 2018-12-05 | — | — | EP | disclosed |
| CN-108430993-A | TANK-BINDING KINASE INHIBITOR COMPOUNDS | 吉利德科学公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-106573928-A | 2-aminothiazole derivative or salt thereof | 安斯泰来制药株式会社 | 2017-04-19 | — | — | CN | disclosed |
| US-20170095445-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES OF THE LUNG | RADIKAL THERAPEUTICS INC (US) | 2017-04-06 | — | — | US | disclosed |
| CN-103709151-B | Spiro-compound as hepatitis c inhibitor and its application in medicine | 广东东阳光药业有限公司 | 2017-03-15 | — | — | CN | disclosed |
| US-20050032790-A1 | For example, 1-(2-Amino-4-chlorobenzoyl-D-phenylglycinyl)-4,4'-bispiperidine; for treatment of thrombosis, emphysema, cirrhosis; antiarthritic agents, anticancer agents, antihistamines | LIEBESCHUETZ JOHN WALTER (GB) | 2005-02-10 | — | — | US | disclosed |
| US-20040242656-A1 | Serine protease inhibitors | LIEBESCHUETZ JOHN WALTER (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1289950-B1 | SERINE PROTEASE INHIBITORS | LILLY CO ELI (US) | 2004-09-08 | — | — | EP | disclosed |
| US-20030078438-A1 | Serine protease inhibitors | ELI LILLY AND COMPANY | 2003-04-24 | — | — | US | disclosed |
| EP-1289950-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096296-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
| US-6316623-B1 | USEFUL FOR SCREENING IN BIOLOGICAL ASSAYS IN ORDER TO IDENTIFY PHARMACEUTICALLY USEFUL COMPOUNDS | ISIS PHARMACEUTICALS, INC. | 2001-11-13 | — | — | US | disclosed |
| WO-1995003421-A1 | PROCESS FOR THE ENZYMATIC PREPARATION OF OPTICALLY ACTIVE N-SUBSTITUTED-3-PYRROLIDINOL | DSM N.V. (NL) | 1995-02-02 | — | — | WO | disclosed |
| US-4038390-A | SALTS OF P-DIHYDROXYBENZENE DISULFONIC ACIDS FOR COMBATTING HEMORRHAGES AND FRAGILITY OF THE CAPILLARIES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1977-07-26 | — | — | US | disclosed |
| US-3947448-A | BLOOD COAGULANT, COMBATING CAPILLARY FRAGILITY | LABORATORIOS DEL DR. ESTEVE SA (ES) | 1976-03-30 | — | — | US | disclosed |