Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.55 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.53 |
| ▸ | TUBB | P07437 | 4/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19751491 | 1.00 | TOP2A (0.55) | TOP2ATOP2BKDM4EKMT2AALDH1A1 | |
| SCHEMBL30306119 | 0.92 | TOP2A (0.55) | TOP2ATOP2BKDM4EKMT2AALDH1A1 | |
| SCHEMBL2339241 | 0.92 | TOP2A (0.55) | TOP2ATOP2BKDM4EKMT2AALDH1A1 | |
| SCHEMBL5541223 | 0.92 | TOP2A (0.55) | TOP2ATOP2BKDM4EKMT2AALDH1A1 | |
| SCHEMBL15828544 | 0.90 | TOP2A (0.54) | TOP2ATOP2BKDM4EKMT2AALDH1A1 | |
| SCHEMBL10835611 | 0.90 | TOP2A (0.54) | TOP2ATOP2BKDM4EKMT2AALDH1A1 | |
| SCHEMBL9873615 | 0.88 | TOP2A (0.52) | TOP2ATOP2BKDM4EKMT2AALDH1A1 | |
| SCHEMBL10834348 | 0.87 | TOP2A (0.66) | TOP2ATOP2BKDM4EKMT2AALDH1A1 | |
| SCHEMBL2081327 | 0.87 | CNR1 (0.54) | TOP2ATOP2BKDM4EKMT2AALDH1A1 | |
| SCHEMBL2081331 | 0.87 | CNR1 (0.54) | TOP2ATOP2BKDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |