Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.62 |
| ▸ | KDM5A | P29375 | 16/20 | 0.58 |
| ▸ | KDM5B | Q9UGL1 | 15/20 | 0.58 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20125308 | 0.88 | KDM4C (0.48) | KDM4CKDM5AKDM5B | |
| SCHEMBL16150489 | 0.77 | KDM4C (1.00) | KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16157351 | 0.75 | KDM5A (0.97) | KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16148830 | 0.74 | KDM5A (1.00) | KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16149889 | 0.73 | KDM4C (1.00) | KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16157398 | 0.70 | KDM5A (0.74) | KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16149899 | 0.70 | KDM4C (1.00) | KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL20125329 | 0.69 | KDM4C (0.71) | KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16148987 | 0.69 | KDM5A (1.00) | KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16149299 | 0.67 | KDM4C (1.00) | KDM4CKDM5AKDM5BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968282-B1 | HISTONE DEMENTHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2018-05-09 | — | — | EP | disclosed |