Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.48 |
| ▸ | KDM5A | P29375 | 14/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 10/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20125306 | 0.88 | KDM4C (0.62) | KDM4CKDM5AKDM5B | |
| SCHEMBL16149210 | 0.78 | KDM4C (0.78) | KDM4CKDM5AKDM5B | |
| SCHEMBL16150308 | 0.76 | KDM4C (0.74) | KDM4CKDM5AKDM5BPTPN11HRH4 | |
| SCHEMBL16149305 | 0.75 | KDM4C (0.79) | KDM4CKDM5AKDM5B | |
| SCHEMBL16149664 | 0.74 | KDM5A (0.57) | KDM4CKDM5AKDM5BPTPN11HRH4 | |
| SCHEMBL16150940 | 0.73 | KDM4C (0.78) | KDM4CKDM5AKDM5B | |
| SCHEMBL16149052 | 0.72 | KDM5A (0.79) | KDM4CKDM5AKDM5BPTPN11 | |
| SCHEMBL20125278 | 0.72 | KDM4C (0.57) | KDM4CKDM5AKDM5BHRH4DRD3 | |
| SCHEMBL16150318 | 0.69 | KDM4C (0.80) | KDM4CKDM5AKDM5B | |
| SCHEMBL16149743 | 0.68 | KDM4C (0.81) | KDM4CKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968282-B1 | HISTONE DEMENTHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2018-05-09 | — | — | EP | disclosed |