Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.61 |
| ▸ | KDM5A | P29375 | 5/20 | 0.61 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20125258 | 0.94 | KDM5B (0.59) | KDM5BKDM5ANPY5RKDM4CCCR1 | |
| SCHEMBL16150053 | 0.76 | KDM5B (1.00) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL20125267 | 0.76 | KDM5B (0.65) | KDM5BKDM5ANPY5RKDM4CKDM4A | |
| SCHEMBL5771571 | 0.72 | KDM5A (0.55) | KDM5BKDM5ANPY5RKDM4CCCNT1 | |
| SCHEMBL16149434 | 0.72 | KDM5A (0.73) | KDM5BKDM5AKDM4CCCNT1CDK9 | |
| SCHEMBL15652643 | 0.71 | IKBKB (0.46) | CCR1CCR5CCR8CCNT1CDK9 | |
| SCHEMBL16157369 | 0.70 | KDM5B (1.00) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL20125363 | 0.69 | KDM5B (0.60) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL20125439 | 0.69 | KDM4C (0.75) | KDM5BKDM5AKDM4C | |
| SCHEMBL3957997 | 0.68 | KDM5A (0.47) | KDM5BKDM5ACCNT1CDK9CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968282-B1 | HISTONE DEMENTHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2018-05-09 | — | — | EP | disclosed |