Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 11/20 | 0.66 |
| ▸ | KDM5A | P29375 | 9/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.51 |
| ▸ | KDM4A | O75164 | 5/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20125409 | 0.87 | KDM5B (0.65) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL20125357 | 0.83 | KDM5B (0.57) | KDM5BKDM5AKDM4CKDM4ADAO | |
| SCHEMBL16150067 | 0.80 | KDM5B (1.00) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL20125365 | 0.78 | KDM5A (0.56) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL16149471 | 0.77 | KDM5B (0.78) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL20125358 | 0.76 | KDM5A (0.53) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL20125363 | 0.74 | KDM5B (0.60) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL20125343 | 0.74 | KDM4C (0.49) | KDM5BKDM5AKDM4CKDM4ADAO | |
| SCHEMBL20125266 | 0.74 | KDM5B (0.61) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL19231079 | 0.74 | KDM5B (0.57) | KDM5BKDM5AKDM4CKDM4ADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968282-B1 | HISTONE DEMENTHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2018-05-09 | — | — | EP | disclosed |