Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 15/20 | 0.65 |
| ▸ | KDM5A | P29375 | 14/20 | 0.65 |
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.65 |
| ▸ | KDM4A | O75164 | 8/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20125359 | 0.87 | KDM5B (0.66) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL20125365 | 0.84 | KDM5A (0.56) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL20125343 | 0.83 | KDM4C (0.49) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL20125477 | 0.82 | KDM4A (0.65) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL20125363 | 0.81 | KDM5B (0.60) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL20125358 | 0.80 | KDM5A (0.53) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL16157316 | 0.79 | KDM5B (1.00) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL20125367 | 0.77 | KDM5A (0.69) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL20125266 | 0.77 | KDM5B (0.61) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL20125489 | 0.75 | KDM5B (0.63) | KDM5BKDM5AKDM4CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968282-B1 | HISTONE DEMENTHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2018-05-09 | — | — | EP | disclosed |