Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 10/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20128405 | 0.87 | SPHK1 (0.35) | HRH3SPHK1NISCHLPLLIPG | |
| SCHEMBL5970189 | 0.85 | TLR8 (0.41) | TLR8TLR7 | |
| SCHEMBL20126349 | 0.84 | SPHK1 (0.34) | HRH3SPHK1NISCHLPLLIPG | |
| SCHEMBL20126165 | 0.84 | ACACB (0.40) | HRH3 | |
| SCHEMBL18931596 | 0.82 | HRH3 (0.33) | HRH3TLR8TLR7 | |
| SCHEMBL20126338 | 0.82 | SPHK1 (0.33) | HRH3SPHK1NISCHLPLLIPG | |
| SCHEMBL20126358 | 0.81 | CHKA (0.36) | HRH3NISCHLPLLIPGMCL1 | |
| SCHEMBL20126102 | 0.80 | NISCH (0.39) | SPHK1NISCHLPLLIPGP2RY14 | |
| SCHEMBL20126351 | 0.80 | RARB (0.36) | HRH3MCL1 | |
| SCHEMBL18215479 | 0.80 | SPHK1 (0.39) | HRH3SPHK1NISCHSPHK2LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127654-A1 | PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2018-05-10 | — | — | US | disclosed |
| US-20180127654-A1 | PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127654-A1 | PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | DRD1, PLD1, DRD2 | HRH3 85/4885SPHK1 1054/4885TLR8 1995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.