SCHEMBL20126424

SCHEMBL20126424

CCOc1ccc(Cc2cc([C@@H]3C[C@@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc2Cl)cc1

nearest known ligand 0.65

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 18/20 0.65
SLC5A1 P13866 13/20 0.65
ADRA2A P08913 1/20 0.63
SLC5A11 Q8WWX8 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20126427 1.00 SLC5A2 (0.65) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL20126426 1.00 SLC5A2 (0.65) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL10083222 1.00 SLC5A2 (0.65) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL13259974 0.90 SLC5A2 (0.56) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL13259976 0.90 SLC5A2 (0.64) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL17929392 0.87 SLC5A2 (0.67) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL20126401 0.86 SLC5A2 (0.61) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL20126403 0.86 SLC5A2 (0.61) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL20126402 0.86 SLC5A2 (0.61) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL20126400 0.86 SLC5A2 (0.61) SLC5A2SLC5A1ADRA2ASLC5A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10759729-B2 Compounds for treating diabetes THE CHINESE UNIVERSITY OF HONG KONG (CN) 2020-09-01 US disclosed
US-20180127343-A1 NOVEL COMPOUNDS FOR TREATING DIABETES THE CHINESE UNIVERSITY OF HONG KONG (CN) 2018-05-10 US disclosed
US-20180127343-A1 NOVEL COMPOUNDS FOR TREATING DIABETES THE CHINESE UNIVERSITY OF HONG KONG (CN) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10759729-B2 Compounds for treating diabetes SLC5A2, GPR119, DPP4 SLC5A2 1/4885SLC5A1 4/4885ADRA2A 1995/4885
US-20180127343-A1 NOVEL COMPOUNDS FOR TREATING DIABETES GPR119, SLC5A2, DPP4 SLC5A2 2/4885SLC5A1 5/4885ADRA2A 2019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.