SCHEMBL20127701

SCHEMBL20127701

c1ccc2c(c1)ccc1c(-c3c4ccccc4c(-c4cc5oc6ccc7ccccc7c6c5c5ccccc45)c4ccccc34)cccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.42
AHR P35869 5/20 0.42
MEN1 O00255 2/20 0.42
TP53 P04637 2/20 0.42
CYP2D6 P10635 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
KMT2A Q03164 2/20 0.42
MAPT P10636 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP1A2 P05177 4/20 0.41
HPGD P15428 4/20 0.41
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 3/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
MAPK1 P28482 2/20 0.41
HIF1A Q16665 2/20 0.41
FYN P06241 2/20 0.41
TSHR P16473 2/20 0.41
ERBB2 P04626 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18267009 0.94 AHR (0.43) AHRMEN1TP53CYP2D6CYP2C9
SCHEMBL20127708 0.92 AHR (0.41) AHRMEN1TP53CYP2D6CYP2C9
SCHEMBL20127339 0.91 HSD17B10 (0.43) HPRT1AHRMEN1TP53CYP2D6
SCHEMBL20416572 0.90 AHR (0.37) HPRT1AHRMEN1TP53CYP2D6
SCHEMBL20127710 0.89 AHR (0.43) AHRMEN1TP53CYP2D6CYP2C9
SCHEMBL19080045 0.88 AHR (0.42) AHRMEN1TP53CYP2D6CYP2C9
SCHEMBL22547057 0.88 TDP1 (0.46) HPRT1AHRMEN1TP53CYP2D6
SCHEMBL20127711 0.88 TDP1 (0.41) HPRT1AHRMEN1TP53CYP2D6
SCHEMBL20416524 0.88 AHR (0.38) AHRMEN1TP53CYP2D6CYP2C9
SCHEMBL22541859 0.87 HSD17B10 (0.44) HPRT1AHRMEN1TP53CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 HPRT1 1076/4885AHR 2558/4885MEN1 3297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.