Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20127882 | 0.81 | CA12 (0.46) | CTSKALDH1A1 | |
| SCHEMBL20127876 | 0.81 | EPHX2 (0.51) | EPHX2HPGDNAAAHDAC3FAAH | |
| SCHEMBL17902822 | 0.80 | CA1 (0.51) | CTSK | |
| SCHEMBL19651943 | 0.80 | CA1 (0.51) | CTSK | |
| SCHEMBL20131352 | 0.80 | CA12 (0.45) | CTSKALDH1A1 | |
| SCHEMBL18866874 | 0.77 | TDP1 (0.49) | FAAHEPHX1 | |
| SCHEMBL29419422 | 0.76 | TDP1 (0.46) | EPHX1 | |
| SCHEMBL7988109 | 0.75 | GRIN2D (0.49) | CTSKALDH1A1 | |
| SCHEMBL5063054 | 0.74 | HDAC3 (0.43) | HPGDNAAAHDAC3HTT | |
| SCHEMBL11260446 | 0.74 | EPHX2 (0.69) | EPHX2HPGDNAAAEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127358-A1 | ANTI-INFLAMMATORY DRUG AND USES THEREOF | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2018-05-10 | — | — | US | disclosed |
| US-20180127358-A1 | ANTI-INFLAMMATORY DRUG AND USES THEREOF | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127358-A1 | ANTI-INFLAMMATORY DRUG AND USES THEREOF | CDK2, CCNT2, CCNE2 | EPHX2 1163/4885CTSK 864/4885HPGD 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.