Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19651943 | 0.88 | CA1 (0.51) | CA12CA1CA7CA14RIPK1 | |
| SCHEMBL20131352 | 0.88 | CA12 (0.45) | CA12CA1CA7CA14RIPK1 | |
| SCHEMBL17902822 | 0.88 | CA1 (0.51) | CA12CA1CA7CA14RIPK1 | |
| SCHEMBL7988109 | 0.82 | GRIN2D (0.49) | CA12CA1CA7CA14RIPK1 | |
| SCHEMBL20127883 | 0.81 | EPHX2 (0.49) | CTSKALDH1A1 | |
| SCHEMBL31384541 | 0.80 | RAB9A (0.46) | CA12CA1CA7CA14RIPK1 | |
| SCHEMBL19639251 | 0.79 | HDAC1 (0.52) | LMNARAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL19639418 | 0.78 | GAA (0.41) | CA12CA1CA7CA14CTSK | |
| SCHEMBL7986750 | 0.77 | MMP8 (0.48) | CA12CA1CA7CA14RIPK1 | |
| SCHEMBL7986748 | 0.77 | MMP8 (0.48) | CA12CA1CA7CA14RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127358-A1 | ANTI-INFLAMMATORY DRUG AND USES THEREOF | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127358-A1 | ANTI-INFLAMMATORY DRUG AND USES THEREOF | CDK2, CCNT2, CCNE2 | CA12 4800/4885CA1 4753/4885CA7 4576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.