Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 10/20 | 0.42 |
| ▸ | CA2 | P00918 | 10/20 | 0.42 |
| ▸ | CA9 | Q16790 | 9/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3632373 | 0.98 | PLA2G2C (0.48) | PLA2G2CALDH1A1MCHR1RECQLGLA | |
| SCHEMBL20548023 | 0.98 | PLA2G2C (0.48) | PLA2G2CALDH1A1MCHR1RECQLGLA | |
| SCHEMBL20129041 | 0.98 | PLA2G2C (0.48) | PLA2G2CALDH1A1MCHR1RECQLGLA | |
| SCHEMBL26813058 | 0.98 | PLA2G2C (0.45) | PLA2G2CALDH1A1MCHR1RECQLGLA | |
| SCHEMBL10590732 | 0.98 | PLA2G2C (0.48) | PLA2G2CALDH1A1MCHR1RECQLGLA | |
| SCHEMBL18473044 | 0.97 | PLA2G2C (0.47) | PLA2G2CALDH1A1MCHR1RECQLGLA | |
| SCHEMBL14476452 | 0.97 | ALDH1A1 (0.45) | PLA2G2CALDH1A1MCHR1RECQLGLA | |
| SCHEMBL23611505 | 0.95 | PLA2G2C (0.45) | PLA2G2CALDH1A1MCHR1RECQLGLA | |
| SCHEMBL13672853 | 0.95 | PLA2G2C (0.45) | PLA2G2CALDH1A1MCHR1RECQLGLA | |
| SCHEMBL14201611 | 0.95 | PLA2G2C (0.45) | PLA2G2CALDH1A1MCHR1RECQLGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912699-B2 | Tau-protein targeting compounds and associated | ARVINAS OPERATIONS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-20180125821-A1 | TAU-PROTEIN TARGETING PROTACS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912699-B2 | Tau-protein targeting compounds and associated | MAPT, VHL, CRBN | PLA2G2C 3788/4885ALDH1A1 3804/4885MCHR1 3847/4885 |
| US-20180125821-A1 | TAU-PROTEIN TARGETING PROTACS AND ASSOCIATED METHODS OF USE | CRBN, VHL, UBQLN2 | PLA2G2C 3837/4885ALDH1A1 4249/4885MCHR1 4141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.