Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28117913 | 0.88 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6CACNA2D1ADRA1A | |
| SCHEMBL17376844 | 0.79 | CACNA2D1 (0.41) | TDP1SMN1; SMN2CACNA2D1ADRA1ACACNB3 | |
| SCHEMBL23964029 | 0.78 | TDP1 (0.36) | TDP1SMN1; SMN2SLC22A6CACNA2D1ADRA1A | |
| SCHEMBL17376872 | 0.78 | TDP1 (0.36) | TDP1SMN1; SMN2SLC22A6PGD | |
| SCHEMBL1941442 | 0.78 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6CACNA2D1ADRA1A | |
| SCHEMBL1941444 | 0.78 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6CACNA2D1ADRA1A | |
| SCHEMBL8853350 | 0.78 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6CACNA2D1ADRA1A | |
| SCHEMBL21902741 | 0.77 | RNPEP (0.43) | CACNA2D1ADRA1ACACNB3CACNA1CPGR | |
| SCHEMBL28766663 | 0.77 | GAA (0.39) | TDP1CYP1A2CHRM1 | |
| SCHEMBL14558024 | 0.76 | TDP1 (0.42) | TDP1SMN1; SMN2SLC22A6ADRA1APGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036068-A | Concentrate composition | 巴塞尔聚烯烃意大利有限公司 | 2019-07-19 | — | — | CN | disclosed |
| US-20180127557-A1 | WATER-BASED SEALING COMPOSITIONS WITH AMINOSILANE CROSSLINKERS | ARAMCO SERVICES COMPANY | 2018-05-10 | — | — | US | disclosed |
| CN-102643370-A | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE SPA | 2012-08-22 | — | — | CN | disclosed |