Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28399097 | 0.95 | NAAA (0.56) | NAAATSHRCYP3A4ATMTDP1 | |
| SCHEMBL28400799 | 0.95 | NAAA (0.56) | NAAATSHRCYP3A4ATMTDP1 | |
| SCHEMBL28393389 | 0.95 | NAAA (0.56) | NAAATSHRCYP3A4ATMTDP1 | |
| SCHEMBL28401694 | 0.91 | NAAA (0.56) | NAAATSHRCYP3A4ATMTDP1 | |
| SCHEMBL28843161 | 0.91 | NAAA (0.56) | NAAATSHRCYP3A4ATMTDP1 | |
| SCHEMBL25125762 | 0.89 | NAAA (0.58) | NAAATSHRCYP3A4ATMTDP1 | |
| SCHEMBL28393949 | 0.89 | NAAA (0.58) | NAAATSHRCYP3A4ATMTDP1 | |
| SCHEMBL28393966 | 0.89 | NAAA (0.58) | NAAATSHRCYP3A4ATMTDP1 | |
| SCHEMBL22608994 | 0.89 | NAAA (0.57) | NAAATSHRCYP3A4ATMTDP1 | |
| SCHEMBL11087515 | 0.89 | NAAA (0.57) | NAAATSHRCYP3A4ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180125815-A1 | CDC7 KINASE INHIBITORS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180125815-A1 | CDC7 KINASE INHIBITORS AND USES THEREOF | CDC7, CDC37, CDCA2 | NAAA 3960/4885TSHR 4850/4885CYP3A4 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.