SCHEMBL20133301

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Astemizole SCHEMBL4385	0.91	KCNH2 (1.00)	KCNH2SSTR5EEDLMNAGAA
	SCHEMBL2380395	0.90	KCNH2 (0.84)	KCNH2SSTR5EEDLMNAGAA
	SCHEMBL10428997	0.89	SSTR5 (0.89)	KCNH2SSTR5EEDLMNAGAA
	SCHEMBL22375097	0.89	KCNH2 (0.80)	KCNH2SSTR5EEDLMNAGAA
	[3H]-Astemizole SCHEMBL13109223	0.89	KCNH2 (0.89)	KCNH2SSTR5EEDLMNAGAA
	[3H]-Astemizole SCHEMBL30412778	0.89	KCNH2 (0.89)	KCNH2SSTR5EEDLMNAGAA
	SCHEMBL11480993	0.89	SSTR5 (0.85)	KCNH2SSTR5EEDLMNAGAA
	Desmetheylastemizole SCHEMBL1152697	0.88	KCNH2 (1.00)	KCNH2SSTR5EEDLMNAGAA
	SCHEMBL9580736	0.88	SSTR5 (0.87)	KCNH2SSTR5EEDLMNAGAA
	SCHEMBL11571595	0.88	SSTR5 (0.87)	KCNH2SSTR5EEDLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.