Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129656 | 1.00 | GRM1 (0.44) | GRM1ADAM17KDM4EALDH1A1DPP4 | |
| SCHEMBL20129683 | 0.83 | DPP4 (0.47) | GRM1KDM4EALDH1A1DPP4MEN1 | |
| SCHEMBL12835705 | 0.83 | DPP4 (0.47) | GRM1KDM4EALDH1A1DPP4MEN1 | |
| Hydrochloric Acid SCHEMBL1514528 | 0.81 | DPP4 (0.47) | GRM1KDM4EALDH1A1DPP4MEN1 | |
| Hydrochloric Acid SCHEMBL1514285 | 0.81 | DPP4 (0.47) | GRM1KDM4EALDH1A1DPP4MEN1 | |
| SCHEMBL13176022 | 0.78 | MEN1 (0.59) | GRM1KDM4EALDH1A1MEN1USP2 | |
| SCHEMBL2261269 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1DPP4MEN1USP2 | |
| SCHEMBL23708107 | 0.75 | AR (0.55) | GRM1KDM4EALDH1A1ARGRM5 | |
| SCHEMBL23708047 | 0.75 | AR (0.55) | GRM1KDM4EALDH1A1ARGRM5 | |
| SCHEMBL23702949 | 0.75 | AR (0.55) | GRM1KDM4EALDH1A1ARGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | MTOR, RICTOR, RPTOR | GRM1 1701/4885ADAM17 3606/4885KDM4E 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.