Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129683 | 1.00 | DPP4 (0.47) | DPP4KDM4EALDH1A1PIM1PIM3 | |
| Hydrochloric Acid SCHEMBL1514528 | 0.98 | DPP4 (0.47) | DPP4KDM4EALDH1A1PIM1PIM3 | |
| Hydrochloric Acid SCHEMBL1514285 | 0.98 | DPP4 (0.47) | DPP4KDM4EALDH1A1PIM1PIM3 | |
| SCHEMBL2261269 | 0.91 | KDM4E (0.47) | DPP4KDM4EALDH1A1GRM5MEN1 | |
| SCHEMBL20129652 | 0.87 | GRM1 (0.46) | DPP4KDM4EALDH1A1GRM1GRM5 | |
| SCHEMBL7843992 | 0.85 | PDCD1 (0.42) | DPP4KDM4EALDH1A1GRM5OPRM1 | |
| SCHEMBL7997651 | 0.83 | PDCD1 (0.43) | DPP4KDM4EALDH1A1GRM5 | |
| SCHEMBL3597699 | 0.83 | AR (0.63) | — | |
| SCHEMBL20133877 | 0.83 | GRM1 (0.44) | DPP4KDM4EALDH1A1GRM1GRM5 | |
| SCHEMBL20129656 | 0.83 | GRM1 (0.44) | DPP4KDM4EALDH1A1GRM1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2011025799-A1 | CATHEPSIN C INHIBITORS | GLAXO GROUP LIMITED (GB) | 2011-03-03 | — | — | WO | disclosed |