SCHEMBL20134685

SCHEMBL20134685

CC(O)C(C)(O)CC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.52
CHRM1 P11229 1/20 0.52
TBXA2R P21731 1/20 0.52
ADRA1A P35348 1/20 0.52
CYP2C19 P33261 2/20 0.50
HIF1A Q16665 2/20 0.50
TSHR P16473 2/20 0.50
CYP2D6 P10635 1/20 0.50
CPT2 P23786 2/20 0.41
ACLY P53396 1/20 0.41
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.39
FFAR1 O14842 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TET2 Q6N021 1/20 0.37
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22965333 0.82 HMGCR (0.55) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL28632313 0.78 HMGCR (0.50) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL20702101 0.77 HMGCR (0.48) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL15841664 0.76 HMGCR (0.48) HMGCRCHRM1TBXA2RADRA1ACYP2C19
T-Butylacetic Acid SCHEMBL8426351 0.74 HMGCR (0.50) HMGCRCHRM1TBXA2RADRA1ACYP2C19
Acetic Acid SCHEMBL16320894 0.73 TP53 (0.33) HMGCRCHRM1TBXA2RADRA1ATSHR
SCHEMBL18283302 0.73 ACLY (0.61) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL28502060 0.73 HMGCR (0.44) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL15518117 0.73 CHRM1 (0.44) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL14876931 0.73 CHRM1 (0.44) HMGCRCHRM1TBXA2RADRA1ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3321300-A1 PARTICULATE SOLID COMPOSITE MATERIAL FOR NUCLEIC ACID PURIFICATION COMPRISING MAGNETIC NANOPARTICLES AXAGARIUS GmbH & Co. KG (DE) 2018-05-16 EP claimed
EP-3321300-A1 PARTICULATE SOLID COMPOSITE MATERIAL FOR NUCLEIC ACID PURIFICATION COMPRISING MAGNETIC NANOPARTICLES AXAGARIUS GmbH & Co. KG (DE) 2018-05-16 EP disclosed