Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29688849 | 0.88 | CNR1 (0.41) | — | |
| SCHEMBL20134963 | 0.88 | CNR1 (0.41) | — | |
| SCHEMBL20135277 | 0.80 | CNR1 (0.40) | DGAT1 | |
| SCHEMBL17844426 | 0.76 | KLKB1 (0.34) | KLKB1P2RX7NPC1DGAT1 | |
| SCHEMBL17844574 | 0.74 | CHRM4 (0.35) | KLKB1DGAT1 | |
| SCHEMBL20135368 | 0.73 | CNR1 (0.41) | EPHX2 | |
| SCHEMBL17844648 | 0.72 | NPC1 (0.36) | KLKB1P2RX7NPC1DGAT1 | |
| SCHEMBL20135506 | 0.71 | CNR1 (0.41) | — | |
| SCHEMBL28672490 | 0.70 | PIM1 (0.30) | — | |
| SCHEMBL492579 | 0.70 | F2RL1 (0.34) | KLKB1NPC1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321256-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2018-05-16 | — | — | EP | disclosed |