Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.62 |
| ▸ | INPPL1 | O15357 | 8/20 | 0.39 |
| ▸ | INPP5A | Q14642 | 5/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | INPP5B | P32019 | 2/20 | 0.36 |
| ▸ | PGK1 | P00558 | 3/20 | 0.34 |
| ▸ | PGK2 | P07205 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135780 | 0.86 | SRC (0.43) | SRCCYP3A4 | |
| SCHEMBL20365073 | 0.84 | SRC (0.42) | SRC | |
| SCHEMBL8388017 | 0.83 | SRC (0.60) | SRCINPPL1INPP5AAKT1INPP5B | |
| SCHEMBL18388279 | 0.78 | MEN1 (0.44) | SRCCYP3A4 | |
| SCHEMBL10504348 | 0.76 | AKR1B1 (0.41) | SRCCYP3A4MAPT | |
| SCHEMBL6551606 | 0.72 | CYP3A4 (0.38) | SRCESR1CYP3A4MAPT | |
| SCHEMBL5074713 | 0.71 | SRC (0.66) | SRCINPPL1INPP5AAKT1INPP5B | |
| SCHEMBL20906675 | 0.71 | GAA (0.37) | SRCCYP3A4 | |
| SCHEMBL21001639 | 0.70 | MAPT (0.39) | SRCMAPT | |
| SCHEMBL20906749 | 0.70 | MCL1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319972-A1 | 1,3-DIPOLAR COMPOUND BEARING A PHOSPHORUS-CONTAINING GROUP AND A DIPOLE CONTAINING A NITROGEN ATOM | Compagnie Générale des Etablissements Michelin (FR) | 2018-05-16 | — | — | EP | disclosed |