Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.44 |
| ▸ | POLRMT | O00411 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135845 | 1.00 | TMPRSS2 (0.44) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL17712216 | 0.93 | TMPRSS2 (0.42) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL23711118 | 0.93 | TMPRSS2 (0.42) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL18666880 | 0.92 | TMPRSS2 (0.41) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL25512406 | 0.92 | TMPRSS2 (0.41) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL17712282 | 0.92 | TMPRSS2 (0.41) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL22342702 | 0.91 | TMPRSS2 (0.41) | TMPRSS2POLRMT | |
| SCHEMBL22342701 | 0.91 | TMPRSS2 (0.41) | TMPRSS2POLRMT | |
| SCHEMBL20550745 | 0.90 | TMPRSS2 (0.40) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL18605958 | 0.90 | TMPRSS2 (0.40) | TMPRSS2POLRMTRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3212174-B1 | METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2018-05-16 | — | — | EP | disclosed |